WHAT CAUSES MANIC DEPRESSION (OR BIPOLAR DISORDER)?

                           
The exact cause of manic depression is not known, but it is believed to be a combination of biochemical, genetic and psychological factors.

Biochemistry

Research has shown that this disorder is associated with a chemical imbalance in the brain, which can be corrected with appropriated medication.

Genetics / Hereditary

Bipolar disorder tends to run in families. Researchers have identified a number of genes that may be linked to the disorder, suggesting that several different biochemicals problems may occur in bipolar disorder (just as there are different kinds of arthritis). However, if you have bipolar disorder and your spouse does not, there is only a 1 in 7 chance that your child will develop it. The chance may be greater if you have a number of relatives with bipolar disorder or depression.

Biological Clocks

Mania and depression are often cyclical, occurring at particular times of the year. Changes in biological rhythms, including sleep and hormone changes, characterise the illness. Changes in the seasons are often associated triggers.

Psychological Stress

People who are genetically susceptible may have a faulty “switch-off” point – emotional excitement may keep escalating into mania: setbacks may worsen into profound depression.

Sometimes a stressful life event such as a loss of a job, marital difficulties, or a death in the family may trigger an episode of mania or depression. At other times, episodes occur for no apparent reason.

Research continues to be needed to identify more clearly the causes, of manic depression and to find better ways of treating it.

The earlier treatment is started, the more effective it may be in preventing future episodes.
                              
 Very effective treatments for bipolar disorders are available.